Osteoarthritis Thumb
Conditions
Brief summary
Single blinded PRP vs. Corticosteroid vs. Placebo (normal saline) intra-articular injection for basal joint arthritis.
Interventions
Platelet Rich plasma
DRUGCorticosteroid injection
Kenalog
OTHERNormal Saline
Control Group - Placebo
Sponsors
Kettering Health Network
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Masking description
Patients will be blinded to therapy they receive
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Stage 1-3 osteoarthritis of the basal joint
Exclusion criteria
* Patients with Stage 4 1st carpometacarpal joint arthritis as described by Eaton * Patients who have received a corticosteroid injection in the last year to the 1st CMC joint on the proposed study side * Patients who have scaphotriquetral, radioscaphoid, or scaphotrapezial osteoarthritis * Patients who have concurrent DeQuervain's tenosynovitis or intersection syndrome or have been treated for either of these in the last 3 months * Patients undergoing evaluation of cervical radiculopathy * Patients with fibromyalgia or inflammatory rheumatic disease * Patients with Pressier disease, Kienbock's, or avascular necrosis of the scaphoid * Patients with any history of primary or secondary bone tumor * Patients that are pregnant or terminally ill
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Disabilities arm shoulder and hand score | 1 year | functional score |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pinch Strength | 1 year | Objective measurement |
Countries
United States
Outcome results
None listed