Partial Dentin Caries Removal
Conditions
Brief summary
eligible teeth will be randomly divided into two groups to be treated with incomplete caries excavation (A), where (A1) represents teeth to be treated with application of Nano silver fluoride solution on remaining carious dentin prior to final permanent glass ionomer restoration application, (A2) represents comparator group to be restored without Nano silver fluoride application prior to restoration. Every participant will receive both the intervention and control treatment. Image of radiographic density of remaining carious dentin will be evaluated using PSP plate at baseline immediately after restoration and after 6 months after restorative procedures. The null hypothesis tested is that application of Nano silver fluoride solution prior to glass ionomer restoration will not increase radiopacity of the underlying dentin treated by incomplete carious removal technique compared to that of direct glass ionomer restoration without prior application of Nano silver fluoride.
Interventions
prepared Nano-silver fluoride could have the capability to arrest caries. As its Nano silver particles have an antimicrobial activity against Mutans Streptococci and Lactobacilli; the main pathogens involved in the development of carious lesions. In addition, its fluoride component is well known to enhance remineralization and inhibit bacterial activity. So, Nano silver fluoride could be a promising solution to combat residual bacteria in tooth cavity with effective remineralization potential on remaining carious dentin
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Intervention model description
split mouth randomized clinical trial
Eligibility
Sex/Gender
ALL
Age
16 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients presenting with at least 2 teeth with active carious lesions limited to the occlusal surface of molars at risk of pulp exposure during direct complete excavation (primary caries lesion involving more than half of the entire dentin thickness determined radiographically). * Signs and symptoms indicative of pulp vitality, i.e. a positive response to thermal stimulation during a cold test * Absence of apical pathosis, clinical diagnosis of pulp exposure, fistula, swelling of periodontal tissues.
Exclusion criteria
* Teeth with spontaneous pain or sensitivity to percussion. * Teeth with periodontal lesions, internal or external root resorption, mobility of tooth, sinus opening, or abscessed tooth. * Radiographic examination revealed, interrupted or broken lamina dura, widened periodontal ligament space, periapical radiolucency. * patients with systemic medical conditions * pregnant females
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Caries remineralization. (Mineral density) | six months | using Density measurement tool in the Digora software |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| dentin bridge formation. | six months | Linear measurement tool in the Digora software in Mm |
Countries
Egypt
Outcome results
None listed