Depressive Disorder
Conditions
Keywords
Agomelatine, Depression, Intraocular pressure
Brief summary
Agomelatine is a melatonin drug used to treat depressive disorder. Agomelatine may also some effects on ocular pressures. In this study, we aimed to demonstrate that melatonin decreases intraocular pressures when given depressive patients.
Detailed description
Melatonin has been shown to be effective to decrease intraocular pressure in experimental animal researches. Agomelatine is a melatonin derivative drug approved for the treatment of depression, which is also available in our country. Depending on animal experiments, it can be assumed that agomelatine can decrease intraocular pressure. Demonstrating that agomelatine is effective to reduce eye pressure may give a concurrent treatment of depressive patients with glaucoma. With this it may be possible to treat both diseases at the same time with single drug. In this study, the researchers intended to investigate the changes in ocular tension in normotensive depressive patients treated with agomelatine.
Interventions
DRUGAgomelatine 25 MG Oral Tablet
We will treat our patients with Agomelatine tablet of 25 mg.
Sponsors
Kahramanmaras Sutcu Imam University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 66 Years
Healthy volunteers
No
Inclusion criteria
* Depressive patients suitable for Agomelatine therapy for the treatment of their primary disease.
Exclusion criteria
\- Any past history of ocular surgery, ocular trauma or existing ocular diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Intraocular pressure | One month | mmHg |
Countries
Turkey (Türkiye)
Outcome results
None listed