Diabetes
Conditions
Brief summary
The objective of the study is to determine how wild blueberry consumption affects glucose regulation, gastrointestinal hormones and satiety in healthy adults.
Detailed description
Healthy men and women (ages 21 - 65 years) were recruited to take part in a randomized, placebo controlled crossover design study. Subjects were screened to determine their health status (e.g. height, weight, body mass index, blood pressure and medical history). Subjects were randomly assigned to a sequence of two treatments with two study periods. The treatments are frozen wild blueberries and a placebo developed to match calories and fiber of the frozen wild blueberries. The subjects were asked to avoid high polyphenol foods in their typical diet for 7 days and consume one of the two treatments as a dietary intervention. After the seventh day subjects consumed a test meal along with either the wild blueberry or placebo. Blood was collected to determine glucose and satiety hormone levels.
Interventions
OTHERBlueberry
Blueberry - 150 grams wild blueberries (whole fruit)
OTHERPlacebo
Placebo - matched for calories and fiber
Sponsors
University of Prince Edward Island
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
21 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Male or female
Exclusion criteria
* BMI \< 20 and \> 30 kg/m² * Pregnant women or women who plan on becoming pregnant during the study * Postpartum women * Lactating women * Diabetes Mellitus * Kidney disease * Liver disease * GI Disease * Certain cancers * Smokers * Blueberry allergies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Glucose (mmol/L) | Change from baseline 0 hours and 2 hours | Plasma glucose |
Countries
Canada
Outcome results
None listed