Extended Application of Intraoperative Parathyroid Scores System(IPSS) in Thyroidectomy

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03191344

Acronym

IPSS

Enrollment

300

Registered

2017-06-19

Start date

2017-07-01

Completion date

2019-07-01

Last updated

2018-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative Parathyroid Scores System

Keywords

Intraoperative Parathyroid Scores System, total thyroidectomy, thyroid cancer, hypoparathyroidism, prediction

Brief summary

after established the Intraoperative Parathyroid Scores System (IPSS) for thyroidectomy we further extented the clinical value of Intraoperative Parathyroid Scores System in Treatment decisions of calcium treatment time and improve recognition skills of parathyroid in Clinicians

Detailed description

IPSS includes transplantation Parathyroid Scores and in situ Parathyroid Scores, the investigators will establish the Intraoperative Parathyroid Scores System by parathyroid size and Blood supply, and recording IPSS, according to certain rules. We expand IPSS, including the description of the location of parathyroid after postoperative.Parathyroid hormone and calcium were test in d0, d1, d14, d60 post operation. The correlation between Intraoperative Parathyroid Scores and PTH calcium were calculated, and ROC curve and logistic regression were tested for the prediction value.and after that we further evaluate the relationship Between IPSS and calcium supplement time.and Whether IPSS enhance ability of parathyroid recognition for clinical doctors.

Interventions

BEHAVIORALwith IPSS

all patient in one group use IPSS to record the parathyroid status. the other group operation as ordinary. record the parathyroid status in verbal description

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 60 Years

Healthy volunteers

Inclusion criteria

1. postoperative pathology confirmed as thyroid papillary carcinoma; 2. for the first time to undergo thyroid surgery, no history of neck surgery and external radiotherapy; 3. preoperative serum calcium, parathyroid hormone levels were normal; 4. intraoperative and postoperative clinical data integrity, standardized follow-up patients; 5. parathyroid is a tumor violation.

Exclusion criteria

1. serious underlying disease; 2. age greater than 60 years of age or combined with arteriosclerotic disease; 3. patients with postoperative loss; 4. patients with parathyroid disease.

Design outcomes

Primary

Measure	Time frame	Description
Differences of parathyroid records between IPSS and TD	1 year	The percentage of recorded integrity of the parathyroid gland and the number of recognizable parathyroids were compared between the two groups.

Secondary

Measure	Time frame	Description
The effect of IPSS on the level of parathyroid recognition of surgeons	1 year	Comparison of the number of parathyroid gland found in the pathology and the number of postoperative hypoparathyroidism between the two groups
differences of the number of parathyroid glands found in the pathology betwen IPSS and TD	1 year	differences of the number of parathyroid glands found in the pathology betwen IPSS and TD

Other

Measure	Time frame	Description
The Predictive Value of IPSS for Intravenous and Oral Calcium duration	1 year	Comparison of the correlation between IPSS values and intravenous calcium supplementation and oral calcium supplementation time.

Countries

China

Contacts

Primary ContactBO WANG, MS

wangbo@fjmu.edu.cn13705947900

Backup Contactwenxin ZHAO, MD

zhaowx@fjmu.edu.cn13365910359

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026