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Variation in Fluids Administered in Shock

Observation of Variation in Fluids Administered and Characterization of Vasopressor Requirements in Shock

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03190408
Acronym
VOLUME
Enrollment
1639
Registered
2017-06-16
Start date
2017-09-01
Completion date
2018-02-01
Last updated
2020-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shock

Brief summary

To conduct a multicenter observational cohort study to determine the variability in fluid resuscitation in shock in a broad range of areas in hospitals and treatment areas.

Interventions

OTHERFluids

Fluids Administered in Shock

Sponsors

Montefiore Medical Center
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age ≥ 18 years admitted to the participating hospital. * Patients in the emergency department, intensive care unit, PACU, or any hospital floor. For patients not in the ICU, there must be plans to transfer to an intensive care unit when an ICU bed is available for patient. * Patients with shock as defined by: * Need for vasopressor (dopamine, norepinephrine, or epinephrine at any dose) to keep MAP \> 65 mmHg Or * Systolic BP \< 90 mmHg

Exclusion criteria

* Patients previously enrolled into this study. * Patients who were in the operating room at time of shock and fluid bolus. * Patients admitted to an ICU after cardiac surgery Patients with primarily cardiogenic shock as etiology for their shock * Patients transferred from another hospital or emergency room to the study hospital.

Design outcomes

Primary

MeasureTime frameDescription
Method used to guide volume resuscitation7 daysCharacterize the method used to guide volume resuscitation and vasopressor use in patients with shock

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026