Control, Population
Conditions
Keywords
bone age measurement, skeletal age measurement, ultrasound, x-Ray
Brief summary
Aiming to validate the use of bone age determined by ultrasound (BAUS) in Brazilian children, normal control students will be studied. X-Ray bone age (RXBA) and BAUS will be determined in 500 children and adolescents of both genders, with chronological age varying from 6-16 years. Concordance analysis and the correlation between both BA determination methods will be performed.
Detailed description
Bone age is a valuable method to recognize the maturation status of development and growth. Classical analyses is performed by using the Greulich and Pyle X-Ray measurement. Such analyses have some restrictions such as intra- and inter observer variability, and variable synchronicity of bone maturation. Bone age determined by ultrasound (BAUS) has been indicated as a fast and reproducible method, allowing decimal BA determination and avoiding the need for X-Ray. Our aim is to validate the BAUS method in Brazilian normal controls. School students of both genders, with age varying from 6 to 16 years will be included.
Interventions
None listed
Sponsors
Faculdade de Ciências Médicas da Santa Casa de São Paulo
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
6 Years to 16 Years
Healthy volunteers
Yes
Inclusion criteria
* absence of chronic illness and drug ingestion
Exclusion criteria
* any chronic disease or medicine use * body mass index: \< -2SDS or \> +2SDS * stature : \< -2SDS or \> +2SDS
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| bone age determination by ultrasound (BAUS) | chronological ages between 6 and 16 years of age | Determination of bone age in years by employing a ultrasound device |
Countries
Brazil
Contacts
Primary ContactCarlos A Longui, MD; PhD
Backup ContactCristiane Kochi, MD
Outcome results
None listed