Bone Metastases, Surgery
Conditions
Brief summary
To provide treatment guidelines for patients with long bone metastatic disease based on observational study and to propose an algorithm to guide orthopedic surgeons in decision-making for these patient.
Detailed description
The objectives of this study were to examine clinical outcomes after reconstruction with intramedullary fixation (IMN) or endoprosthetic reconstruction (EPR) with a specific focus on (1) the rate of complication or failure; (2) differences in complication rates by anatomic site; (3) functional results as assessed by the Musculoskeletal Tumor Society System (MSTS); (4) differences in complication rate between patients treated with INM versus EPR; and (5) differences in survival in patients with metastatic bone disease based on disease-specific, laboratory, and demographic information.
Interventions
Surgical treatment of impending or pathologic fracture in the extremities
Sponsors
Istituto Ortopedico Rizzoli
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Inclusion criteria
* bone metastases of the extremity
Exclusion criteria
* bone metastases of the spine
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Clinical outcomes after treatment of long bone metastases with intramedullary nail versus endoprosthetic reconstruction | 1 year | The objectives of this study were to examine clinical outcomes after reconstruction with intramedullary nail versus endoprosthetic reconstruction with a specific focus on differences in complication rate between patients treated with intramedullary nail versus endoprosthetic reconstruction |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Survival in patients undergoing surgery for metastatic bone disease | 1 year | Provide a reliable and objective means of estimating survival in patients with metastatic bone disease based on disease-specific |
Countries
Italy
Outcome results
None listed