Crystalloids for AKI in Shock Patients

Different Crystalloids on the Incidence of Acute Kidney Injury in Shock Patients

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03188614

Enrollment

Registered

2017-06-15

Start date

2017-08-01

Completion date

2018-10-01

Last updated

2017-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shock

Keywords

shock, crystalloid, acute kidney injury

Brief summary

Fluid resuscitation is important in shock therapy, but the choice of fluids, especially the choice of crystalloid is under debate. It is said that normal saline is related to hyperchloremia， which might lead to acute kidney injury. Thus the hypothesis of the study is to explicit whether balanced salt solution could reduce the incidence of acute kidney injury when compared with normal saline.

Interventions

DRUGFluid resuscitation

The placebo group is resuscitated with normal saline, the experimental group is resuscitated with balanced fluid.

Study design

Allocation

RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Shock patients

Exclusion criteria

* History of chronic renal failure

Design outcomes

Primary

Measure	Time frame	Description
Incidence of acute kidney injury	28-day	Diagnosis of acute kidney injury

Secondary

Measure	Time frame	Description
Usage of renal replacement of therapy	28-day	Usage of CRRT

Contacts

Primary ContactJingyuan Xu, Docotor

xujingyuanmail@163.com13851417209

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026