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Cardiac Complication After Vascular Surgery

The Reasons of Repolarization Disturbances Disclosure in Vascular Surgery

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03188341
Acronym
CCVS
Enrollment
100
Registered
2017-06-15
Start date
2010-12-31
Completion date
2017-06-30
Last updated
2017-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Aneurysm, Abdominal, Cardiac Complication, Peripheral Arterial Disease, Ventricular Arrythmia

Keywords

vascular surgery, repolarization disturbances, cardiac complications, high risk patient, high risk procedure

Brief summary

The vascular surgery is a highest risk procedure when considering postoperative complications associated with the cardiovascular system. The leading clinical presentation is acute hemodynamic decompensation. However, one of the possible pathomechanisms might be repolarization disturbances. Many of perioperative risk factors of cardiac complications are modifiable. The identification may help in the global perioperative risk reduction. Aim: The aim of the study was an identification of the factors which may release clinically overt repolarization disturbances. Methods: The study group consisted of 100 patients, diagnosed with abdominal subrenal aortic aneurysms or peripheral arterial disease scheduled for an elective open vascular surgery procedure. The authors investigated whether age, gender, comorbidities or some perioperative factors (including hemodynamic, metabolic or genetic) were related to the occurrence of clinically concealed repolarization disturbances or clinically disclosed cardiac complications in postoperative time up to 30 day and one year after vascular surgery procedure.

Detailed description

Vascular surgery is thought as the highest risk procedure in the context of cardiac complications. The range may include acute coronary syndrome, acute circulatory failure, severe arrhythmias, syncope and sudden cardiac death. The patient population is considered as a high risk, too. Popular calculators used for risk stratifications are based on preoperative patient's history and some general laboratory results. However, general status of the patient changes dynamically during vascular procedures leading to acquired increased risk. For this reason, sole preoperative risk prediction based on standard calculators is unsuitable and suboptimal. Advanced monitoring systems may record some temporary disturbances (e.g. ventricular repolarization disturbances), which may be asymptomatic. The clinical significance in postoperative risk prediction of such observations remains undefined. On the other hand, many of perioperative cardiac complications are caused by modifiable factors. The identification may help in the global perioperative risk reduction.

Interventions

OTHERvascular surgery procedure

* an elective open vascular surgery procedure * ECG Holter recording during the procedure and 24 hours after operation (continuous electrocardiographic tracing (digital Holter ECG monitor)

Sponsors

Pomeranian Medical University Szczecin
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* adult patients diagnosed with abdominal subrenal aortic aneurysms or peripheral arterial disease scheduled for an elective open vascular surgery procedure

Exclusion criteria

* heart stimulation, * atrioventricular and intraventricular conduction defects, * atrial fibrillation recorded before of the study, * antiarrhythmic drug treatment (except beta-blockers), * unoptimal patient general status (uncontrolled diabetes, active infection) * reoperation * emergency operations

Design outcomes

Primary

MeasureTime frameDescription
cardiac complicationsup to 30 days after vascular procedurecardiac complications according to European Society of Cardiology

Secondary

MeasureTime frameDescription
cardiac complicationsduring surgical procedurecardiac complications according to European Society of Cardiology

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026