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Flash-free Brackets and Dental Plaque

Do Adhesive Flash-free Brackets Affect Bacterial Plaque? A Randomized Controlled Clinical and Microbiological Assessment

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03187483
Enrollment
45
Registered
2017-06-15
Start date
2014-01-31
Completion date
2014-09-30
Last updated
2017-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Orthodontic Treatment

Brief summary

This study aimed to compare flash-free bracket system with conventional adhesive-coated bracket system in patients with maxillary crowding.

Detailed description

Aim: The aim of this split-mouth study was to compare conventional and adhesive flash-free-bracket systems in terms of plaque retention, white spot lesion formation, biomarker levels and select microbes in gingival crevicular fluid (GCF). Materials & Methods: Thirty-seven systemically healthy patients (18 males, 19 females) with the age range of 13-18 years were involved in this split-mouth study. Clinical evaluations, quantitative light-induced fluorescence (QLF) imaging, GCF and plaque samplings were performed at baseline and at 1-, 2-, 3-months. QLF was repeated following debonding, GCF samples were analyzed by immunoassay and real-time PCR for the biomarker and bacteria content. Data were analyzed by Wilcoxon on dependent samples.

Interventions

PROCEDUREorthodontic treatment

orthodontic treatment in maxillary crowding

Sponsors

Ege University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender
ALL
Age
13 Years to 18 Years
Healthy volunteers
Yes

Inclusion criteria

* being systemically healthy * having 4-7 mm maxillary crowding with a maximum of 2 mm linear displacement of contact points and non-extraction treatment planning.

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
development of white spot lesion (WSL)1 monthWSL is the first sign of caries

Secondary

MeasureTime frameDescription
plaque accumulation around the brackets1 monthplaque deposits cause gingival inflammation
microbial composition around the brackets1 monthpresence of pathogen bacteria is important

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026