Left Ventricular Dyssynchrony in Multipole Pacing

The Impact of Multipole Pacing (MPP) on Left Ventricular Dyssynchrony in Patients With Cardiac Resynchronization Therapy (CRT) - a Real-Time Three Dimensional Echocardiography Approach

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03187470

Enrollment

Registered

2017-06-15

Start date

2017-03-01

Completion date

2018-05-31

Last updated

2023-03-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart Failure，Congestive

Brief summary

Left ventricular dyssynchrony will be assessed by echocardiography using different programming of an implantable cardioverter defibrillator.

Detailed description

Left ventricular dyssynchrony will be assessed by echocardiography using different programming of an implantable cardioverter defibrillator using a quadripolar left ventricular lead.

Interventions

DEVICEDifferent programming of a CRT defibrillator

Different programming of a CRT defibrillator using pacing modalities of a quadripolar left ventricular lead

Study design

Allocation

NON_RANDOMIZED

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Indication for the implantation of a defibrillator with cardiac resynchronisation therapy

Exclusion criteria

* Cardiac surgery, acute coronary syndrome / myocardial infarction, percutaneous coronary intervention within the past 4 weeks * Indication for coronary artery revascularisation * Atrial fibrillation with insufficient rate control * ASA (American Society of Anesthesiologists) class V or cardiogenic shock * age \<18 years, pregnancy, tutelage * inability to understand the patient consent for or study refusal * anticipated insufficient echocardiographic image quality

Design outcomes

Primary

Measure	Time frame	Description
Left ventricular dyssynchrony	15 minutes	Left ventricular dyssynchrony

Secondary

Measure	Time frame	Description
left ventricular ejection fraction	15 minutes	left ventricular ejection fraction

Countries

Germany

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026