Intervention Strategy in Chronic Obstructive Pulmonary Disease With Anxiety and Depression

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03187249

Enrollment

500

Registered

2017-06-14

Start date

2017-06-15

Completion date

2020-12-31

Last updated

2017-06-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anxiety, COPD, Depression

Brief summary

Anxiety and depression have negative effect on outcomes of chronic obstructive pulmonary disease (COPD). Intervention strategy including behavioral-cognitive therapy and pulmonary rehabilitation are promising in improving life quality, disease symptom and outcomes. But there's not standard algorithm in China so far. The study aims to compare the effectiveness of these interventions and develop an intervention algorithm of anxiety and depression in COPD.

Interventions

BEHAVIORALCognitive Behavioral Therapy

12 weeks cognitive-behavioral lessons, once a week

BEHAVIORALPulmonary Rehabilitation Therapy

12 weeks pulmonary rehabilitation exercise

BEHAVIORALCombined Therapy

cognitive-behavioral lessons and pulmonary rehabilitation exercise for 12 weeks

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

No minimum to 80 Years

Healthy volunteers

Inclusion criteria

* Stable COPD patients with mild or moderate anxiety and depression

Exclusion criteria

* Patients with bronchial asthma or other severe pulmonary diseases or having received pulmonary surgery in 6 months * Patients with tumor history during past 5 years * Patients with COPD exacerbations during past 4 weeks * Participants in clinical trials * Patients in pregnancy or breastfeeding * Patients unable to complete questionaire independently * Patients older than 80 years old * Patients receiving long-term domiciliary oxygen therapy

Design outcomes

Primary

Measure	Time frame	Description
Hospital Anxiety and Depression Scale	12 weeks	total score

Secondary

Measure	Time frame	Description
moderate and severe COPD exacerbations	3 years	total times
modified British medical research council score	3 years	total score
COPD assessment test score	3 years	total score

Countries

China

Contacts

Primary ContactJiangna Han, MD

13520053104@139.com13520053104

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026