Tobacco Use
Conditions
Brief summary
Participants will complete a phone screen and then one laboratory session. After completing in-person screening assessments, eligible participants will complete additional questionnaires. Participants will then choose an e-liquid flavor to use for the rest of the session. Participants will then sample two e-liquids that vary in nicotine content from little or no nicotine to a moderate level of nicotine, and questionnaires evaluating the subjective effects of each one. Participants will then complete a preference assessment where they choose between the two e-liquids. Participants will be blind to the nicotine contents.
Interventions
BEHAVIORALE-liquid sampling and preference assessment
Participants will sample two different e-liquids that vary in nicotine content, complete questionnaires about each one, and then choose between the two e-liquids in a preference assessment task.
Sponsors
National Institute on Drug Abuse (NIDA)
Wake Forest University Health Sciences
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* At least 18 years old * Daily cigarette smoking * Have tried vaping devices on a minimum of one lifetime occasion
Exclusion criteria
* Unwilling to use a vaping device during the session * Break alcohol level \> 0.01 (g/dL) * Pregnant, trying to become pregnant, or breastfeeding * Systolic BP greater than or equal to 160 mm/Hg or below 90 mm/Hg * Diastolic BP greater than or equal to 100 mm/Hg or below 50 mm/Hg * Heart rate greater than or equal to 105 bpm or lower than 45 bpm * A current upper respiratory infection, recent cardiac event (in the last year), Buerger disease, irregular heartbeat or arrhythmia within the last year, previous allergic or adverse reaction to nicotine
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Product Evaluation Questionnaire | One Day | Ratings of the two e-liquids on a self-report questionnaire |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Preference Assessment | One Day | Choices of each of the two e-liquids on a preference assessment |
| Perceived Health Risk Questionnaire | One Day | Personal Health Risk Ratings about each of the two e-liquids |
| Vaping Purchase Task | One Day | Hypothetical estimates of consumption of each of the e-liquids across a variety of prices |
Outcome results
None listed