Exploratory Study of the Interest of MRI Susceptibility Weighted Imaging for the Pre-operative Assessment of Pelvic Endometriosis Extent

Status

Completed

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03186820

Acronym

EndoSWI

Enrollment

Registered

2017-06-14

Start date

2017-06-19

Completion date

2018-04-24

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis

Keywords

Endometriosis, Magnetic resonance imaging (MRI), Susceptibility-weighted imaging (SWI)

Brief summary

Knowledge of the precise location of endometriosis is essential for a successful surgical treatment. MRI Susceptibility-Weighted Imaging (SWI-MRI) yields high sensitivity for blood by-products detection. Since endometriosis lesions are haemorrhagic, and therefore rich in blood by-products such as hemosiderin, SWI-MRI could be useful in the pre-operative assessment of endometriosis, especially in superficial peritoneal lesion detection. The purpose of our study is to evaluate the performance of SWI-MRI for the preoperative work-up of endometriosis

Detailed description

Pelvic endometriosis is a cause of pelvic pain, dysmenorrhea, urinary symptoms and infertility. MRI is considered as the best imaging technique to detect and to predict the extent of the disease. Susceptibility Weighted Imaging is routinely performed to identify haemorrhagic lesions in brain MRI protocols and has proven to be a sensitive technique to detect blood by-products. A pelvic MRI protocol including SWI will be performed in all women addressed for diagnostic assessment or pre-operative work-up of endometriosis.

Interventions

OTHERSusceptibility Weighted Imaging as 3D SWAN sequence

Susceptibility Weighted Imaging as 3D SWAN sequence

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Intervention model description

Prospective monocentric comparative study

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adult woman (over 18yrs old) addressed for diagnostic assessment or pre-operative work-up of endometriosis; * Informed signed consent * Affiliated or beneficiary of a social security system

Exclusion criteria

* Patient \<18yrs old * Pregnant or nursing woman * Patient under legal protection * Contraindication to MRI

Design outcomes

Primary

Measure	Time frame	Description
Interest of MRI Susceptibility Weighted Imaging	Baseline (MRI) and day of surgery	The diagnostic use of SWI-MRI will be assessed through: * the number of endometriotic locations, which are both identified with SWI-MRI and confirmed by surgery. * the sensitivity, specificity, and predictive values of MRI. * signal intensities of each endometriotic location found in surgery on T1 weighted sequence (presence of a high signal intensity) and SWI (presence of a low signal intensity)

Secondary

Measure	Time frame	Description
Deep forms of endometriosis	Baseline (MRI) and day of surgery	MRI findings will be compared to surgical findings
Superficial forms of endometriosis	Baseline (MRI) and day of surgery	MRI findings will be compared to surgical findings

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 2, 2026