Acute-On-Chronic Liver Failure in Zagazig University Hospitals

ACLF in Zagazig University Hospitals

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03184636

Acronym

ACLF

Enrollment

300

Registered

2017-06-12

Start date

2017-07-01

Completion date

2018-08-11

Last updated

2018-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute-On-Chronic Liver Failure

Keywords

ACLF, SOFA, Zagazig university

Brief summary

Rationale: To identify the prevalence of Acute-on-chronic liver failure in Zagazig University Hospitals. The question of the research: How much the prevalence of Acute-on-chronic Liver Failure in Zagazig University Hospitals? The aim of the work: The aim of the study is to identify the presence of Acute-on-chronic Liver Failure in Zagazig University Hospitals Objectives: To estimate the prevalence of Acute-on-chronic Liver Failure in Zagazig University Hospitals. Subjects and Methods: I . Technical Design: * Site of the study: Gastroenterology and Hepatology Unit- Zagazig University Hospitals * Sample size: ''all patients admitted to Gastroenterology and Hepatology Unit with the criteria of ACLF according to EASL-AASLD from June 2017 to December 2017 were included in this study''. II . OPERATIONAL DESIGN: * Type of the study: a prospective study. * Full medical history - taking. * Full clinical examination. * Laboratory investigations including Routine laboratory investigation CBC, Liver functions test, kidney functions test and prothrombin time III. Administrative Design: * Approvals obtained for performing the study from the official or governmental department. * An ethical committee from the faculty of medicine and patients included in the study. Results: Collected data will be presented in tables and suitable graphs and analyzed according to standard statistical methods

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* all patients admitted to Gastroenterology and Hepatology Unit with the criteria of ACLF according to EASL-AASLD will be included in this study.

Exclusion criteria

* no any

Design outcomes

Primary

Measure	Time frame	Description
improvement of the patients score according to SOFA score (AASLD and EASL guidelines)	24 weeks from first recruiting	follow up of participants until the patients recover

Secondary

Measure	Time frame	Description
death of the patient	24 weeks from first recruiting	due to the severity of acute on chronic failure, the death of patients is expected

Countries

Egypt

Outcome results