Intubation
Conditions
Brief summary
In the operating room, most intubation procedures (IP) are scheduled and performed on hemodynamically stable patients. In the ICU, IP is frequently performed in emergent patients, because of unstable hemodynamics and/or acute respiratory failure, and complicated by a subsequent cardiovascular collapse. Transthoracic echocardiography (TTE) has become readily available in most ICUs for several years. Echocardiography enables to perform a noninvasive hemodynamic evaluation (cardiac function and volemia status). We hypothesized that performing a TTE prior to IP may help to predict cardiovascular collapse and its components.
Interventions
None listed
Sponsors
University Hospital, Brest
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Patient requiring endotracheal intubation
Exclusion criteria
* Age \< 18 yrs * Pregnancy * Amputation of a lower limb * Passing leg raising contraindication: intracranial hypertension with invasive monitoring, fracture of the pelvis or limbs * Patients under administrative protective measures * Severe cardiovascular collapse before intubation * Severe cardiogenic pulmonary oedema
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Subsequent cardiovascular collapse related to intubation | Within 15 minutes of intubation | Mean arterial pressure drop \< 60 mmHg |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Ultrasound parameters to predict fluid responsiveness | 30 minutes before intubation, less than 30 minutes after intubation, 1 minutes after lifting legs and 3 hours after intubation | Transthoracic echocardiography parameters to predict fluid responsiveness |
Countries
France
Outcome results
None listed