Skip to content

Effectiveness of Pre-Consultation Medication Reconciliation Service in Reducing Unintentional Medication Discrepancies During Transition of Care From Hospital Discharge to Primary Care Setting

Effectiveness of Pre-Consultation Medication Reconciliation Service in Reducing Unintentional Medication Discrepancies During Transition of Care From Hospital Discharge to Primary Care Setting- A Randomised Controlled Trial

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03181906
Enrollment
200
Registered
2017-06-09
Start date
2016-03-11
Completion date
2017-04-30
Last updated
2017-06-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medication Adherence, Medication Administered in Error

Keywords

medication discrepancy, primary care, transition of care

Brief summary

This study evaluates the the effectiveness of pre-consultation Medication Reconciliation Service in reducing unintentional medication discrepancies among patients who discharged from hospital to primary care.

Detailed description

Medication discrepancies during care transition were common. Many factors contribute to the risk of medication discrepancies. Despite medication reconciliation service being practiced in the hospital setting, there was limited knowledge on its effectiveness in the primary care setting. This study aims to evaluate the effectiveness of a pre-consultation medication reconciliation service in reducing medication discrepancies in patients who transit from hospital to primary care. Adult patients who made their first visit to the polyclinics following a recent hospital discharge and were prescribed with 5 or more chronic medications were randomised to 2 groups. Pre-consultation medication reconciliation by a pharmacist was carried out for the intervention group. Outcome was assessed by a different pharmacist who was blinded to the randomised allocation. The control group underwent usual care without a pre-consultation medication reconciliation.

Interventions

OTHERPre-Consultation Medication Reconciliation

Medication reconciliation service to be done for participants randomised to the intervention group

Sponsors

National Healthcare Group, Singapore
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
21 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

1. Age 21 years and older 2. Patient or primary caregiver was able to provide informed consent 3. Patient or primary caregiver was English, Mandarin or Malay speaking 4. Patient was able to self-administer medications, or accompanied by a caregiver who assisted in administering medications 5. Patient was prescribed 5 or more chronic medications 6. The day of the study visit was the first follow-up visit in National Healthcare Group Polyclinics for chronic disease management after recent discharge from a local public hospital

Exclusion criteria

1. Residents of nursing home 2. The day of the study visit was for acute illness consult 3. Unwilling to consent to a 30-day follow-up phone call.

Design outcomes

Primary

MeasureTime frameDescription
Unintentional medication discrepancies1 dayAny unintentional medication discrepancies after doctor's consultation

Secondary

MeasureTime frameDescription
Types of medication discrepancies1 dayType of medication discrepancies, by a validated instrument by Claeys et al, (Claeys C, Neve J, Tulkens PM, Spinewine A. Content Validity and Inter-Rater Reliability of an Instrument to Characterize Unintentional Medication Discrepancies.Drugs & Aging. 2012 July; 29(7): 577-91.)
Causes of medication discrepancies1 dayCauses of medication discrepancies, by a validated instrument by Claeys et al, (Claeys C, Neve J, Tulkens PM, Spinewine A. Content Validity and Inter-Rater Reliability of an Instrument to Characterize Unintentional Medication Discrepancies.Drugs & Aging. 2012 July; 29(7): 577-91.)
Medication adherence30 daysMedication adherence by The 8-item Morisky Medication Adherence Scale
30-day re-hospitalisation30 daysrate of re-hospitalisation 30 days after the study visit

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026