Stellate Ganglion Block
Conditions
Keywords
Stellate ganglion block Tourniquet reaction
Brief summary
To investigate the influence of stellate ganglion block on tourniquet response during surgery in patients undergoing elective lower limb Department of orthopedics.
Detailed description
Select elective general anesthesia in 100 cases of lower extremity Department of orthopedics surgery patients were randomly divided into SGB group and control group, SGB group received anesthesia before the right stellate ganglion block intervention, the control group underwent right deltoid muscle injection, changes in hemodynamics in two groups were recorded in heart rate, blood pressure, and before anesthesia, after intubation 3min 1H, a tourniquet, tourniquet release before and after tourniquet release 3min, 30min, changes in blood physiological analysis. The effect of stellate ganglion block on tourniquet response during perioperative period was observed.
Interventions
PROCEDUREStellate ganglion block
Stellate ganglion block with 1% lidocaine 10ml
PROCEDUREcontrol group
Deltoid muscle injection with 1% lidocaine 10ml
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes
Inclusion criteria
* American Society of anesthesiologists Grade 1-3 Patients * undergoing lower limb surgery under general anesthesia * should be treated with tourniquet
Exclusion criteria
* Tourniquet application time is less than 1h, greater than 1.5h * Abnormal coagulation function * perioperative application of hormone * lidocaine allergy * can not cope with nerve block * nerve block failure * minimally invasive surgery
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| postoperative pain | hour 1、hour 6、hour 24、hour 48 after operation | VAS score |
| blood pressure | 2 hours in perioperative period | mmHg |
| heart rate | 2 hours in perioperative period | bpm |
| Lac | One minute after the radial artery puncture, the tourniquet was applied for 1 hours and the tourniquet was released 3 minutes after the tourniquet release 30 minutes | blood gas analysis mmol/L |
| cortisol | One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet | ELISA ng/ml |
| norepinephrine | One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet | ELISA nmol/L |
| ET-1 | One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet | ELISA ng/L |
| MDA | One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet | ELISA nmol/ml |
| SOD | One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet | ELISA μg/L |
| IL-6 | One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet | ELISA pg/ml |
| cTn-T | One minute after the radial artery puncture, one minute after intubation, tourniquet application 1 hour, one minute before tourniquet, loose after a tourniquet for 3 minutes, 30 minutes after a tourniquet | ELISA μg/L |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Complication of puncture | 2 hours in perioperative period | bleeding、nerve injury、 |
Countries
China
Contacts
Primary ContactTie Xu, MD
Backup ContactShuangshuang Meng, bachelor
Outcome results
None listed