Efficacy of Enhanced Recovery After Surgery Pathway for Total Mastectomy

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03181139

Acronym

ERAS_Breast

Enrollment

386

Registered

2017-06-08

Start date

2013-07-01

Completion date

2016-04-30

Last updated

2017-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer Female, Mastectomy

Keywords

Enhanced Recovery after Surgery (ERAS), Fast-track surgery, Pec Blocks, Mastectomy

Brief summary

Retrospective analysis of pre and post-Enhanced Recovery after Surgery for Total mastectomy pathway implementation.

Detailed description

Retrospective analysis of pre- and post-Enhanced Recovery after surgery for total mastectomy pathway implementation in patients at Mount Zion Hospital. We examined perioperative opioid consumption, pain scores, post-operative nausea and vomiting, benzodiazepine use, length of stay for the time period before and after implementation of an Enhanced Recovery after Surgery pathway for Total mastectomy. Pathway features included preoperative acetaminophen and gabapentin, minimizing opioids, postoperative NSAIDs, Pecs blocks, and aggressive postoperative nausea and vomiting prophylaxis.

Interventions

OTHERERAS pathway for Total Mastectomy

Enhanced Recovery after Surgery (ERAS) pathway for Total Mastectomy

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* female patients at least 18 years old undergoing total skin sparing mastectomy at University of California San Francisco Mount Zion hospital

Exclusion criteria

* patients undergoing concurrent bilateral salpingo-oophorectomy, flap reconstruction

Design outcomes

Primary

Measure	Time frame	Description
perioperative opioid consumption	through study completion (average of 1 year)	perioperative opioid consumption

Secondary

Measure	Time frame	Description
Post-operative nausea and vomiting (PONV)	through study completion (average of 1 year)	incidence post-operative nausea and vomiting
postoperative benzodiazepine use	through study completion (average of 1 year)	amount of benzodiazepines used postoperatively for treatment of muscle spasm
Length of stay (LOS)	through study completion (average of 1 year)	Length of stay
Pain score	through study completion (average of 1 year)	highest pain score perioperatively
Surgery duration	through study completion (average of 1 year)	length of surgery (min)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026