Hip Dysplasia
Conditions
Brief summary
The study will assess the outcomes of patients treated with concomitant hip arthroscopy at the time of periacetabular osteotomy (PAO) for patients with hip dysplasia compared with patients treated with PAO alone.
Detailed description
There are currently no absolute indications for intraarticular assessment at the time of periacetabular osteotomy (PAO). Based on investigators' review of the literature and experience, patients who may benefit from intraarticular assessment are those with radiographic or MRI evidence of damage where an intraarticular inspection may help in determining whether a PAO is a reasonable procedure, those with mechanical symptoms likely related to labral pathology, round ligament or cartilage problems and those with hip dysplasia and cam deformities with limited range of motion that may benefit from femoral head neck junction osteochondroplasty. However, despite these relative indications today there is no clear evidence to suggest that these patients will do better than those that do not have intraarticular work done. Hence, the objective of this project is to determine whether intraarticular work at the time of PAO surgery leads to improved pain and function when compared to patients that do not undergo intraarticular work at the time of PAO.
Interventions
PROCEDUREPeriacetabular osteotomy
The Bernese periacetabular osteotomy has become the osteotomy of choice in North America for correction of the dysplastic hip. The ability to position the acetabular component in a specifically desired position for each individual patient improves joint biomechanics, restores joint balance and stability, and offloads the structures at risk for damage such as the labrum and the adjacent articular cartilage.
PROCEDUREPeriacetabular osteotomy with hip arthroscopy
An intraarticular assessment with hip arthroscopy (HA) at the time of periacetabular osteotomy allows the surgeon to assess and treat the associated labral and chondral pathology and allows the surgeon to treat abnormalities of the femoral head junction.
Sponsors
Mayo Clinic
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Masking description
Patients will be randomized in a 1:1 fashion. The first arm will be the "PAO alone" group who will receive a standard periacetabular osteotomy (PAO) on the day of surgery. The second arm will be the "PAO + HA" group who will receive a PAO and hip arthroscopy (HA) on the day of surgery. Any pathology if present that can be corrected with the arthroscope (cartilage and labral abnormalities) will be addressed. This will be followed by a standard PAO. Patients from both groups will have dressings placed in the location of hip arthroscopy portals to remain blinded to the treatment arm during the perioperative period. Only patients in the PAO + HA group will have incisions and sutures under these dressings. The dressings will come off for all patients after 2 weeks, which is standard of care. All other study team members will remain unblinded.
Eligibility
Sex/Gender
ALL
Age
15 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* Diagnosis of hip dysplasia (DDH) electing periacetabular osteotomy (PAO) for treatment * Skeletally mature * Age 15 - 55 * Tonnis Grade 0 or 1 osteoarthritis (minimal or no arthritis) * Ability to receive a standard of care preoperative (magnetic resonance imaging) MRI arthrogram of the hip
Exclusion criteria
* Pregnant women * Previous surgery about the hip * Patients receiving PAO for acetabular retroversion in the absence of DDH * Previous hip arthroscopy to address intra-articular pathology
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean score of Hip Disability and Osteoarthritis Outcome (Hoos) | 1 year follow-up time point | Score ranges from 0-100 with higher scores representing better function. |
| Mean score of Western Ontario and McMaster Universities Arthritis Index (WOMAC) | 1 year follow-up time point | The scores range from 0-4 in 24 different categories that are broken up into three subcategories: pain, stiffness and physical function. |
| Mean score of University California Los Angeles (UCLA) activity assessment | 1 year follow-up time point | Measured on a 1-10 scale: 1) wholly inactive, dependent on others; 2) mostly inactive, restricted to minimal activities of daily living; 3) sometimes participate in mild activities such as walking, limited housework, or shopping; 4) regularly participate in mild activities; 5) sometimes participate in moderate activities such as swimming and unlimited housework or shopping; 6) regularly participate in moderate activities; 7) regularly participate in active events such as bicycling; 8) regularly participate in very active events such as bowling or golf; 9) sometimes participate in impact sports such as jogging, tennis, or skiing, or heavy labor; and 10) regularly participate in impact sports. |
| Mean score of the Marx Activity Scale (MARX) | 1 year follow-up time point | Score is measured from 0-4. |
Countries
United States
Contacts
CONTACTCody Wyles, MD
CONTACTLauren Cole
PRINCIPAL_INVESTIGATORRafael Sierra, MD
Mayo Clinic
Outcome results
None listed