Concentrated Growth Factors, Furcation Defects, Periodontal Regeneration
Conditions
Brief summary
Objective: To compare the effect of guided tissue regeneration (GTR) + concentrated growth factors (CGF) + bone graft and CGF + bone graft in the treat of II° furcations of human mandibular molars. Methods: At least thirty II°furcation involvements in mandibular molars will be included and randomly divided into two groups. The experimental group will accept GTR + CGF + bone graft therapy, and the control group will accept CGF + bone graft therapy. The clinical examination and cone beam computed tomography (CBCT) will be performed at baseline and 1 year post-surgery.
Interventions
PROCEDUREGTR + CGF + bone graft
Guided tissue regeneration (GTR) combined with CGF and bone graft to treat mandibular furcation involvements
PROCEDURECGF + bone graft
CGF combined with bone graft to treat mandibular furcation involvements
Sponsors
Jing Qiao
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* II° furcation involvements in mandibular molars * after periodontal therapy.
Exclusion criteria
* not healthy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| clinical measurement | 1 year | Probing depth |
| clinical parameter | 1 year | clinical attachment loss |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| radiographic parameter | 1 year | cone beam computerized tomographic scanning |
Countries
China
Contacts
Primary Contactqiao jing, doctor
Outcome results
None listed