Impacted Third Molar Tooth
Conditions
Keywords
hydrocortisone, third molar, oral surgery, postoperative pain, edema
Brief summary
The investigators set out to develop a clinical trial in order to test the topical use of hydrocortisone as a intraoperative irrigant solution. As this route of administration as well as being low cost and not add new steps to the surgical procedure, can contribute to an improved quality of life in the postoperative period of patients undergoing extraction of third molars.
Detailed description
Third molars are the teeth with a higher prevalence of failure in eruption and surgery for extraction of these impacted teeth is one of the most commonly procedures performed by the oral and maxillofacial surgeon. In most cases these are not traumatic procedures, however factors such as patient age, habits, degree of tooth impaction and surgeon experience can influence the surgical trauma and therefore the postoperative period could include swelling and pain of varying magnitudes which can significantly affect the patient's quality of life. The study is designed as a prospective, randomized, placebo-controlled, split-mouth crossover trial. All the patients will be informed of the experimental methodology and signed a institutionally approved consent form. The study is been conducted in compliance with Declaration of Helsinki (1989), and was revised by the Institutional Ethical Committee (protocol 1.167.908).
Interventions
During the third molar extraction the hydrocortisone solution will be used in the test group
During the third molar extraction the saline solution will be used in the control group
Sponsors
Study design
Eligibility
Inclusion criteria
* Health patients of any sex, with symmetric bilateral bone-impacted mandibular third molars requiring surgical removal, and with no history of allergy to the drugs used in this study.
Exclusion criteria
* Use of analgesic or anti-inflammatory drugs 24 hours before the surgery. * Pregnant or breastfeeding patients, * Use of other drugs beyond of that one's prescribed by the researchers;
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Edema | From the preoperative moment to the second postoperative day | Change in edema measures |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Pain | Up to 2 days (amount of analgesic medication intake form the immediate postoperative moment to the second postoperative day) | Quantitative evaluation (amount of analgesic medication intake) |
Countries
Brazil