Emergence Agitation
Conditions
Brief summary
The aim of this randomized double-blinded study is to determine whether transition to propofol for 3 min at the end of sevoflurane anaesthesia reduces the incidence of EA in children undergoing genito-urinary paediatric surgeries.
Interventions
DRUGPropofol
propofol 1 mg/kg IV bolus will be given to the patient with a further 2 mg/kg administered manually over the next 3 min prior to the patient leaving the OR
DRUGNormal saline
Normal saline will be administered manually over the next 3 min prior to the patient leaving the OR
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
3 Years to 8 Years
Healthy volunteers
No
Inclusion criteria
1. Children Aged 3 - 8 years 2. ASA (I - II) 3. Genito-urinary Surgeries: hernia, varicocele, etc.
Exclusion criteria
1. Patients or parental refusal 2. Allergy to Propofol or egg products; or a family history of malignant hyperthermia 3. Operating time more than 60 minutes 4. Performance of any other procedure under the same anaesthetic 5. Presence of co-morbidities or congenital anomalies 6. mental disease, neurologic disease, treatment with sedatives, full stomach, or indication for rapid sequence induction.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Emergence Agitation | 30 min after emergence | The incidence of EA according to the Watcha scale (defined as a score ≥3 at any time in the 30 min after emergence) |
Countries
Egypt
Outcome results
None listed