Clinical Study of the Presence of Trichomonas Tenax and Entamoeba Gingivalis in Patients With Periodontitis

Preliminary Clinical Study of the Presence of Trichomonas Tenax and Entamoeba Gingivalis in Patients With Periodontitis Consulting to CHU of Nancy, in Periodontal Department.

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03178838

Acronym

Paro-Proto 2

Enrollment

Registered

2017-06-07

Start date

2013-12-03

Completion date

2014-11-11

Last updated

2017-11-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis, Adult

Brief summary

The buccal cavity presents microorganismes whose the number and composition vary with oral hygiene and medical context (pathologies and associated drug therapies) of the patient. More than 1200 bacterial species have been identified, and among them, 400 are inhabitants of the sub-gingival biofilm. Among all these microorganismes, only 20 species participate to the etiopathogenesis of periodontal diseases.Some are recognised as major periodontopathogens other play unclear role in this pathology. They belong respectively to the red and orange complex of Socransky et al. (1998). Other microorganismes such as virures, yeasts and protozoans could potentially impact the emergence and development of periodontal diseases. The presence of protozoans in periodontitis have been investigated in this study.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Adults \> 18 years-old * Consulting in periodontal department of CHU, Nancy * Patient with moderate to severe periodontitis * At least 2 periodontal sites with PPD≥ 4mm and One healthy site * No scaling root planning in the last 6 months * Patients insured under the French social security system

Exclusion criteria

* Pregnant patients * Patients with antibiotic therapy, and/or all medecines which could modify the buccal microbiota in the last 6 months * Tooth with endodontic periapical lesion * Patients having a scaling root planning in the last 6 months * Patient with guardianship

Design outcomes

Primary

Measure	Time frame
Presence of protozoans	baseline

Secondary

Measure	Time frame
Periodontal pocket depth (mm)	baseline
Clinical attachment loss (mm)	baseline
Plaque and gingival index	baseline
Mobility of the tooth (Yes/No)	baseline
Presence of bleeding on probing (Yes/No)	baseline

Outcome results