Implant Placement in Mandibular Molar Xenograft Versus PRF

Immediate Implant Placement With Deproteinized Bovine Bone (Tutogen) Versus Placement of Platelet-rich Fibrin as a Space Filling Material in Mandibular Molars. Randomized Clinical Trial.

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03177356

Enrollment

Registered

2017-06-06

Start date

2016-07-31

Completion date

2017-07-31

Last updated

2017-06-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Edentulous Alveolar Ridge

Keywords

Platelet rich fibrin,xenograft

Brief summary

20 recruited patients indicated for immediate implant placement in mandibular molar patients are divided into 2 groups each group contain 15 patients, one group assigned for placement of bovine bone after molar extraction and immediate implant placement, while the other group we use Platelet-rich fibrin as space filling material.

Interventions

PROCEDUREextraction,implant placement,PRF

Surgical extraction of mandibular molar using periotome and forceps followed by implant placement in inter-septal bone. Then a blood sample is withdrawn from patient and placed in the centrifuge. Then Platelet-Rich fibrin is placed in the extraction socket as space filling material

PROCEDUREExctraction,Implant placement,Bone graft

Surgical extraction of mandibular molar using extraction forceps and periotome followed by implant placement in interseptal bone. De-proteinized bovine bone graft material is placed as space filling material

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

1. Patients with non-restorable mandibular molars 2. Both sexes \-

Exclusion criteria

* • Heavy smokers more than 20 cigarettes per day.5 * Patients with in sufficient interseptal bone height and width * Patients with systemic disease that may affect normal healing. * Patients with completely resorbed buccal cortical plate.

Design outcomes

Primary

Measure	Time frame	Description
Patient satisfaction	1 week post operative	evaluation of postoperative complications regarding pain and oedema

Secondary

Measure	Time frame	Description
implant stability	will be measure intraopertively immediately after insertion of the implants and will be measure one more time 6 months after 1st operation at the time of exposure of implants	measurement of implant stability using osstell device
amount of bone gained or lost around the implants	6 months postoperative	two cone beam computed tomography (CBCT) will be taken for the patient, one immediate postoperative and the other 6 months after the operation then the height of bone gained or lost around the implants will be assessed by superimposing the same section in the two CBCTS

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026