Different Chemotherapy Protocols Combined With Intensity Modulated Radiation Therapy in Patients With Locally Advanced Nasopharyngeal Carcinoma

the General Hospital of PLA

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03177174

Enrollment

150

Registered

2017-06-06

Start date

2017-06-12

Completion date

2020-02-01

Last updated

2020-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug-Related Side Effects and Adverse Reactions

Keywords

locally advanced nasopharyngeal carcinoma, Concurrent chemoradiotherapy, Toxic reaction

Brief summary

This study was to evaluate the efficacy ,toxic reaction and safety of different chemotherapy combined with radiotherapy on patients with locally advanced nasopharyngeal carcinoma.

Interventions

DRUGCisplatin

radiotherapy combined with Chemotherapy Drugs, Cancer

DRUGDocetaxel

Docetaxel

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Patients \> 18, \<70 years old, with locally advanced nasopharyngeal carcinoma.

Exclusion criteria

* patients who had accepted radiotherapy before patients with any ather types of cancer

Design outcomes

Primary

Measure	Time frame	Description
changes in toxic reaction	5 years	incidence rate of the toxic reaction between three groups

Secondary

Measure	Time frame	Description
over survival	5 years	differences of over survival rate between three groups

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026