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Prescribe to Save Lives

Implementation to Motivate Physician Response to Opioid Dependence in HIV Settings

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03175640
Acronym
PTSL
Enrollment
294
Registered
2017-06-05
Start date
2017-07-12
Completion date
2019-12-31
Last updated
2020-12-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Drug Overdose, Opioid-Related Disorders

Brief summary

The U.S. is in the midst of an epidemic of opioid overdose deaths. The common use of opioids among persons living with HIV, along with their common use of benzodiazepines, has resulted in high rates of opioid overdose among this population. This study will test the implementation of evidence-based training, mentoring, technical support, and academic detailing to encourage HIV physicians to adopt evidence-based interventions to reduce overdose risk and treat opioid addiction.

Interventions

The implementation intervention includes peer-to-peer training, post-training outreach, proactive expert support, and assistance with addressing environmental barriers.

Sponsors

National Institute on Drug Abuse (NIDA)
CollaboratorNIH
The Miriam Hospital
CollaboratorOTHER
Boston Medical Center
CollaboratorOTHER
Rhode Island Hospital
CollaboratorOTHER
Baystate Medical Center
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

Clinicians and staff of HIV practice sites that: * Receive Ryan White Funding; * Treat adults with HIV; * Have 3 or more prescribing clinicians; * Have an electronic medical record (EMR) with an electronic medication list.

Exclusion criteria

* Sites located in states with fewer than 500 Persons Living With HIV (PLWH) will be excluded

Design outcomes

Primary

MeasureTime frameDescription
Change in naloxone prescribing behaviorbaseline to 6 monthsNumber of clinicians that prescribe naloxone. This information will be collected from electronic medical record (EMR) data.

Secondary

MeasureTime frameDescription
Change in perception about pharmacotherapy for opioid use disorder; 12-monthbaseline to 12 monthsOpinions About Medication Assisted Treatment (OAMAT) survey
Change in prescribing motivation; 6 monthsbaseline to 6 monthsChange in Motivation Scale
Change in perception about pharmacotherapy for opioid use disorder; 6-monthbaseline to 6 monthsOpinions About Medication Assisted Treatment (OAMAT) survey
Change in prescriber trainingbaseline to 12 monthsNumber of prescribers that have completed buprenorphine training.
Change in buprenorphine prescribing behaviorbaseline to 12 monthsPrevalence of buprenorphine prescription. This information will be collected from EMR data.
Change in prescribing motivation; 12 monthsbaseline to 12 monthsChange in Motivation Scale

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026