PREsurgical Cognitive Evaluation Via Digital clockfacEdrawing

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03175302

Acronym

PRECEDE

Enrollment

25240

Registered

2017-06-05

Start date

2018-06-28

Completion date

2027-05-31

Last updated

2026-08-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive Dysfunction

Keywords

cognitive processes, perioperative cognition, neurocognitive impairment

Brief summary

This study leverages a modernized digital version of a well-known cognitive screening tool to examine pre and post operative cognitive function after surgery in adults age 65 years or more. Machine learning algorithms will be applied to the hospital wide standard of care cognitive metric to identify risk for post-operative cognitive complications.

Detailed description

This proposal innovatively leverages a brief but informative digital test with machine learning to examine the subtlety of pre-surgery cognition within an extremely large number of older individuals screened preoperatively within an academic tertiary medical center. It also incorporates a unique group of well characterized non-surgery peers for demographic matching to assist with normal versus abnormal machine learning analyses.

Interventions

BEHAVIORALdigital cognitive testing

The digital testing is hypothesized to identify latent features for differentiating cognitively impaired presurgical patient subgroups

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

65 Years to No maximum

Healthy volunteers

Inclusion criteria

* \>/= 65 years of age * screening within the University of Florida (UF) Health Preoperative clinic * presurgical cognitive screening with the digital Clock Drawing Tool (dCDT)

Exclusion criteria

* \< 65 years of age * did not complete screening within the UF Health Preoperative clinic * did not complete the presurgical cognitive screening with the digital Clock Drawing Tool (dCDT)

Design outcomes

Primary

Measure	Time frame	Description
Control and pre-surgery differences between digital behaviors	up to one year	Measure range of digital outcome differences

Secondary

Measure	Time frame	Description
Predictive validity of digital behaviors on outcome	up to 1 year	Digital tools will predict clinician reported events
Change over time in digital behavior between groups	up to 6-weeks	Surgery group and control group differences from baseline to 6-weeks

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORCatherine Price, Ph.D.

University of Florida

PRINCIPAL_INVESTIGATORPatrick Tighe, MD, MS