Dexmedetomidine Premedication in Children

The Effect of Oral Dexmedetomidine Premedication On Preoperative Cooperation and Emergence Delirium In Children Undergoing Dental Treatment

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03174678

Enrollment

100

Registered

2017-06-02

Start date

2017-03-01

Completion date

2017-05-25

Last updated

2017-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Premedication

Keywords

Dexmedetomidine, child, premedication, emergence delirium, dental treatment

Brief summary

The aim of this retrospective study was to detect the effectiveness of 1µg/kg oral dexmedetomidine premedication on preoperative cooperation and emergence delirium of the the young children underwent complete dental treatment.

Detailed description

One Hundred children between the ages 2-6 years of ASA I status underwent full mouth dental rehabilitation were enrolled in the study. Group Dex (n=50) received 1µg/kg dexmedetomidine in apple juice and Group control (n=50) received apple juice only. Patients' Ramsey Sedation Scale (RSS), The Parental Seperation Anxiety Scale (PSAS), Mask Acceptance Scale (MAS) and Post anesthesia emergence delirium scale (PAEDS) and hemodynamic parameters were noted from their patient file. Premedication period was 45 minutes and measurements of RSS and hemodynamic parameters were recorded in baseline and every 15 minutes until the patients were transferred to the operating room. The data were analysed using the Kruskal-Wallis test, two sample t- tests, chi-square tests and ANOVA.

Interventions

DRUGDexmedetomidine

1µg/kg dexmedetomidine oral

OTHERapple juice

apple juice

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Investigator)

Masking description

Investigator

Intervention model description

Retrospective study

Eligibility

Age

2 Years to 6 Years

Healthy volunteers

Yes

Inclusion criteria

* The inclusion criteria is age between 2 to 6 years and American Society og Anesthesiology (ASA) grade 1.

Exclusion criteria

* The

Design outcomes

Primary

Measure	Time frame	Description
Ramsey Sedation Score	45 minutes after premedication	Sedation level

Secondary

Measure	Time frame	Description
Parental Separation Anxiety Score	preoperative	Separation anxiety

Other

Measure	Time frame	Description
Mask Acceptance Score	Before induction	Mask acceptance

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 27, 2026