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The Efficiency of Different Oropharyngeal Airways as a Conduit for Fiberoptic Intubation. Comparative Study

The Efficiency of Different Oropharyngeal Airways as a Conduit for Fiberoptic Intubation. Comparative Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03173651
Enrollment
60
Registered
2017-06-02
Start date
2016-06-30
Completion date
2017-05-31
Last updated
2017-06-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fiberoptic Tracheal Intubation

Brief summary

60 Patients were randomly allocated into three equal groups, after induction of general anesthesia one of the three airways included in the study (Modified Williams, Modified Gudle's and LMA MADgic airway) was used as a conduit for endotracheal tube placement using fiberoptic bronchoscopy. Airway insertion time, ease of insertion, adaptation to oral cavity and intubation time was recorded.

Detailed description

The study was conducted in Kasr Alainy hospital, faculty of medicine, Cairo University. After approval of ethical committee and informed written consent from each patient, 60 patient aging above 18 years, ASA I-II , with Ganzouri airway score \<4 and undergoing elective surgeries under general anesthesia were included in the study. Patients were randomly allocated into three equal groups: Group M (GM) (n=20 patients): patient was intubated using LMA MADgic airway. Group W (GW) (n=20 patients): patient was intubated using modified Williams airway. Group G (GG) (n=20 patients): patient was intubated using modified Guedel's airway. Randomization was performed by random computer allocation with numbered closed opaque envelopes. The study was performed by expert anesthesiologist in FOB intubation. In the preparation room, all patients was cannulated with a 20 gauge venous cannula and 0.02mg/kg Midazolam was given. Patient transferred to the operating room and was monitored with non-invasive blood pressure, pulse oximetry and ECG. After preoxygenation using a facemask for 5 min, induction of anesthesia was done with 2mg/kg propofol, 1 μg/kg of fentanyl and 0.6 mg/kg of atracurium. After loss of consciousness the selected airway according to group randomization was inserted into the mouth (size selection and technique of insertion according to manufacturer instruction). Time of insertion defined as the time, in seconds, from touching the patients' mouth with the airway until capnographic confirmation of ventilation by facemask. The ease of insertion was determined by number of attempts of airway insertion. Adaptation of the airway was determined by adequacy of ventilation, fitness to the oral cavity and appearance of successive ETco2 waves. Manual positive-pressure ventilation was then started with 100% oxygen and 1-1.5% isoflurane through the facemask for 3 min until complete muscle relaxation was confirmed (when train-of-four count becomes zero). Loaded FOB was inserted for intubation through the airway, laryngeal view grade was recorded (LVG) using Brimacomb and Berry scale; thereafter, the fiberscope was advanced into the trachea to a level just above the carina and the tracheal tube was railroaded over it. Tracheal intubation could be facilitated by tube rotation, jaw thrust, neck extension or flexion and adjustment of the airway was allawed and was recorded. The intubation time was recorded ; that is, the time from cessation of manual ventilation using a facemask until restarting of ventilation through the tracheal tube. The airway was removed except the LMA MADgic airway which was removed before ETT insertion. The ease of airway removal was evaluated by the anesthesiologist.

Interventions

DEVICEModified Williams airway

This airway used as a conduit for fiberoptic bronchoscopic tracheal intubation in Group W

DEVICEModified Guedle's airway

This airway used as a conduit for fiberoptic bronchoscopic tracheal intubation in Group G

DEVICELMA MADgic airway

This airway used as a conduit for fiberoptic bronchoscopic tracheal intubation in Group M

Sponsors

Kasr El Aini Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
DEVICE_FEASIBILITY
Masking
NONE

Intervention model description

prospective randomized trial

Eligibility

Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes

Inclusion criteria

* ASA physical state I-II Ganzouri airway score less than 4

Exclusion criteria

* ASA physical state III-IV. Patients with Ganzouri airway score more than 4. Patients with risk of aspiration of gastric content. Any anatomical abnormalities or iatrogenic injuries that invalidate Ganzouri airway score.

Design outcomes

Primary

MeasureTime frameDescription
Time of intubationwithin 15 minutes from induction of general anesthesiaThe time from cessation of manual ventilation using a facemask until restarting of ventilation through the tracheal tube

Secondary

MeasureTime frameDescription
Time of insertionwithin 15 minutes from induction of general anesthesiaTime from touching the patients' mouth with the airway until capnographic confirmation of ventilation by facemask
Laryngeal View Gradewithin 15 minutes from induction of general anesthesiaDegree of vocal cord visualization by fiberoptic bronchoscope

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026