Knee Arthroscopy, General Anesthesia, Subarachnoid Block
Conditions
Brief summary
The study evaluates the efficacy of two different anesthetic techniques in patients undergoing unilateral knee arthroscopy. Participants will be randomized to receive either subarachnoid block with 2-chloroprocaine or general anesthesia plus intravenous fentanyl.
Detailed description
The study evaluates the efficacy of two different anesthetic techniques in patients undergoing unilateral knee arthroscopy. Participants will be randomized to receive either subarachnoid block with 2-chloroprocaine or general anesthesia plus intravenous fentanyl. The study evaluates pain scores, opioid utilization and patient satisfaction.
Interventions
PROCEDUREGeneral anesthesia
General anesthesia will be delivered per standard procedure. General anesthesia will include induction with propofol 1-3mg/kg followed by placement of a laryngeal mask airway with maintenance anesthesia of sevoflurane 0.5-1 minimum alveolar concentration (MAC).
PROCEDURESubarachnoid block
Neuraxial anesthesia will be performed at the L2-3 or L3-4 interspace with a 25-gauge Whitacre needle in the sitting position. After free flow of cerebrospinal fluid (CSF), 40-45mg of 2-chloroprocaine will be injected based on patient's height and discretion of attending anesthesiologist, needle withdrawn and the patient placed supine.
Sponsors
Vanderbilt University Medical Center
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
30 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Patients with ASA physical status classification of I, II, or III * Patients without a current diagnosis of chronic pain or chronic opioid use for \> 1-month prior to knee arthroscopy * Patients who are scheduled to undergo unilateral knee arthroscopy * Patients do not have a contraindication to receiving regional anesthesia
Exclusion criteria
* Preexisting sensory or motor deficit in operative extremity * Patients with a contraindication to general anesthesia * Patient undergoing meniscal or ligamentous repair
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain score | Discharge from post anesthesia care unit (PACU) (usually one hour) | Pain score measured with a patient reported 11 point Numeric Rating Pain Scale with 0 indicating no pain and 10 indicating worst pain imaginable. |
| Opioid utilization | Surgical completion to PACU discharge (usually one hour) | Opioid utilization based on amount of opioid medications administered |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient satisfaction with anesthetic | 24 hours after PACU discharge | Patient satisfaction with anesthetic based on 10-item patient satisfaction survey validated for regional and general anesthesia |
Countries
United States
Outcome results
None listed