Body Mass Index and Audiology Function

Effect of Increased Body Mass Index on Auditory Function

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03172663

Enrollment

Registered

2017-06-01

Start date

2018-05-01

Completion date

2019-11-01

Last updated

2017-06-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hearing Loss

Keywords

obesity

Brief summary

Obesity may directly or indirectly lead to hearing loss

Detailed description

Obesity is measured by Body Mass Index.it is calculated by dividing a person's weight in kilograms by the square of height in meters. For children and adolescent. Overweight is defined as Body Mass Index is \<85th percentile \<95th percentile but obesity is defined as body mass index at or above the 95th percentile for children and teens of the same age and sex the increasing in body mass index mass may affect auditory function Directly as adipose tissue secretes hormones and cytokines, proinflammatory cytokines lead to release of obesity-induced inflammation which may directly contribute to end-organ damage Also, Adiponectin, which is thought to have anti-inflammatory and antiatherogenic effects, and associated with favorable lipoprotein profile, independent of BMI and insulin resistance, low plasma concentrations of adiponectin have been associated with obesity in children. In adults, low level of adiponectin has been associated with elevated high-frequency thresholds. Indirectly, by obesity comorbidities including Hypertension, Type 2 diabetes mellitus, Dyslipidemia , Metabolic Syndrome and Cardiovascular Diseases

Interventions

DEVICEpure tone audiometry

for estimate the type and degree of hearing loss

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

10 Years to 40 Years

Healthy volunteers

Yes

Inclusion criteria

It will include 50 subjects whose: * Age ranges from 10 to 40 years old. * Body Mass Index more than the 85th percentile. * male and female will be included

Exclusion criteria

* External or middle ear disease that causes conductive hearing loss such as otitis media, otomycosis, perforated drum, tumors, dislocation of the ossicles. * High environmental noise exposure which causes acoustic trauma such as exploration, fire shots and noise in industries. * ototoxic drug intake such as Aspirin, Aminoglycosides, Erythromycin, Vancomycin Streptomycin, Kanamycin, Neomycin, Gentamycin, Tobramycin, Lasix, Cisplatin, Nitrogen Mustard, and Vincristine, and Quinine. * Major neurological or psychiatric diseases brain tumor, vestibular Schwannoma, stroke, acoustic neuroma, encephalitis, meningitis, and depression.

Design outcomes

Primary

Measure	Time frame	Description
body mass index	20 minutes	if increased body mass index affect auditory function assessed by pure tone audiomertry

Contacts

Primary Contactmohammed salama bakr, Professor

mohamedsalamabakr@yahoo.com1006550289

Backup Contactamira Mohammad Abdel Moneim, Lecturer

Amira_oseily@yahoo.com1095495110

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026