Liver Diseases
Conditions
Brief summary
Non-alcoholic fatty liver disease is the most common cause of chronic liver disease worldwide. It is defined as the accumulation of fat (\>5%) in the liver cells in the absence of excessive alcohol intake or other causes of liver disease including viral, drug-induced, or autoimmune. Non-alcoholic fatty liver disease is a hepatic manifestation of metabolic syndrome.
Interventions
DIAGNOSTIC_TESTglomerular filtration rate
collection of blood sample 5 milliliter for calculation of glomerular filtration rate
Sponsors
Assiut University
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* All non alcoholic fatty liver disease patients evidenced by abdominal ultrasound. * Urine analysis whether normal or renal sedimentation.
Exclusion criteria
1. Alcoholic fatty liver patients. 2. patients known to have diabetes mellitus. 3. patients with other causes of liver disease as viral hepatitis, drug induced,or autoimmune. 4. patients known to have kidney disease. 5. Hypertension. 6. Hyperuricemia. 7. Impaired urea and creatinine patients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The percentage of patients with abnormal laboratory glomerular filtration rate | 1 day | decreased glomerular filtration rate \<60 mL/minute will be considered abnormal |
Countries
Egypt
Contacts
Primary ContactMahmoud Ali, MBBCh
Outcome results
None listed