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Dexmedetomidine and Laparoscopic Surgery

The Effect of Adding Intrathecal Dexmedetomidine on Shoulder Tip Pain During Laparoscopic Ovarian Cystectomy Under Bupivacaine Spinal Anaesthesia. Randomised Controlled Study.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03172065
Enrollment
60
Registered
2017-06-01
Start date
2017-07-01
Completion date
2018-07-09
Last updated
2020-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia Complication

Brief summary

Conventionally General anaesthesia remains the choice for the majority of open abdominal surgical procedures, and regional anaesthesia is preferred only for patients who are at high risk under general anaesthesia . The main reason for selecting spinal anaesthesia as the first choice for laparoscopic cases was its advantages over general anaesthesia which include uniform total muscle relaxation, a conscious patient, economical, relatively uneventful recovery, pain free early postoperative period and the protection from potential complications of general anaesthesia. The main debatable point, however, seems to be the status of respiratory parameters among the two modes of anaesthesia during laparoscopic surgery. In this context it can be stated that spontaneous physiological respiration during spinal anaesthesia would always be better than an assisted respiration as in general anaesthesia. The pneumo-peritoneum induced rise in intra-abdominal pressure including pressure on the diaphragm and carbon dioxide induced peritoneal irritation are the factors to be considered

Interventions

DRUGNormal saline

intravenous flluid

DRUGDexmedetomidine

anaesthetic adjuvants and pain killer medication.

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
FEMALE
Age
20 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

* Elective gynaecological laparoscopic surgery * Age 20-45 yrs * Suspected surgery time 30 minutes * Inflation pressure \<13 Cm H20

Exclusion criteria

* Contraindications to regional block (infection at the needle insertion site) * Altered conscious level. * Pregnancy * Body mass index \>35 * Height \<155 cm * Patients who have difficulty understanding the study protocol

Design outcomes

Primary

MeasureTime frame
occurrence shoulder tip pain48 hours

Secondary

MeasureTime frame
intraoperative haemodynamic stability, et co2, sao2.2 hours

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026