Gastric Varix, Liver Cirrhoses, Portal Hypertension
Conditions
Brief summary
Balloon-occluded retrograde transvenous obliteration (BRTO) has been effective method to manage gastric varices. However, more than one third of patients after BRTO treatment experienced worsening of esophageal varices. The present study was designed to evaluate the effect of post-BRTO propranolol adminstration on the change of esophageal varices.
Interventions
DRUGPropranolol
Propranolol was given after patients with cirrhosis and isolated gastric varices underwent balloon occluded retrograde transvenous obliteration successfully.
Sponsors
West China Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
1. Clinical diagnosis of liver cirrhosis 2. Clinical diagnosis of isolated gastric varices 3. The presenec of spontaneous portosystemic shunt
Exclusion criteria
1. Contradictions to Propranolol 2. Balloon occluded retrograde transvenous obliteration was failed
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Worsening of esophageal varices rate | 3 years | Analysis |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Variceal rebleeding rate | 3 years | Analysis |
| Mortality rate | 3 years | Analysis |
| Worsening of ascites rate | 3 years | Analysis |
Countries
China
Contacts
Primary Contactxuefeng luo
Outcome results
None listed