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Hepatectomy With or Without the Thoraco-abdominal Approach

Hepatectomy With or Without the Thoraco-abdominal Approach: Impact on Perioperative Outcome

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03171428
Enrollment
744
Registered
2017-05-31
Start date
2007-01-01
Completion date
2015-04-01
Last updated
2017-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatectomy, Liver Resection, Liver Tumors, Surgery

Brief summary

The performance of hepatectomy for liver tumors using the thoraco-abdominal approach (TAA) versus the abdominal approach (AA) is still debated. The aim of the study is the analysis of the perioperative outcome of patients operated with or without the TAA for liver tumors.

Detailed description

The prospectively maintained database was queried. A 1:1 propensity score-matched analysis was applied. Among 744 patients, 246 undergoing hepatectomy with TAA and 246 undergoing hepatectomy with AA were compared. These patients were matched for baseline characteristics, underlying liver disease, comorbidity, tumor features, and extent of the resection. The rates of morbidity and mortality were the study endpoints.

Interventions

PROCEDUREHepatectomy

Surgery for liver tumors is the removal of a part of the liver affected by a tumor.

Sponsors

University of Milan
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* First liver surgery; * Any type of malignant liver tumor, including hepatocellular carcinoma on cirrhosis.

Exclusion criteria

* Previous history of liver surgery; * Any type of benign liver tumor; * Incomplete clinical, surgical, pathological or postoperative data; * Patients treated with radiofrequency ablation alone or in combination with surgery were also excluded.

Design outcomes

Primary

MeasureTime frameDescription
Short-term outcome: Occurrence of postoperative complications or death after surgeryWithin 90-days after the operationOccurrence of postoperative complications or death after surgery

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026