Impact of Preemptive Intravenous Ibuprofen on Intraoperative Analgesia in Third Molar Teeth

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03170726

Enrollment

Registered

2017-05-31

Start date

2017-05-15

Completion date

2017-11-15

Last updated

2017-05-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intraoperative Analgesia, Preemptive Intravenous Ibuprofen

Keywords

Preemptive intravenous ibuprofen, Intraoperative analgesia, Third molar tooth surgery

Brief summary

This study was planned to evaluate the analgesic efficacy of preemptive intravenous (iv) ibuprofen on pain occurring during and after the mandibular third molar surgeon

Interventions

DRUGarveles

Intraoperative and postoperative pain values between these three groups will be compared.

DRUGintrafen 800 mg

ibuprofen 800 mg in normal saline 150 cc before operation will be given in 30 minutes. Intraoperative and postoperative pain values between these three groups will be compared.

OTHERplasebos

normal saline 150 cc before operation will be given in 30 minutes. Intraoperative and postoperative pain values between these three groups will be compared.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

20 Years to 35 Years

Healthy volunteers

Inclusion criteria

* Patients who are to be elected third molar tooth extraction * Patients between the ages of 20-35 * Patients who are symptomatic * Third molar tooth angular or horizontal settled patients

Exclusion criteria

* Patients who refuse to participate in the study * Patients under 20 years old, over 35 years old * Patients who are allergic to known non-steroidal anti-inflammatory drugs * Pregnant patients * Patients with severe liver failure, * patients with severe renal insufficiency

Design outcomes

Primary

Measure	Time frame	Description
intraoperative pain as assessed by visual analogue scale	5 month	Assessment of Preemptive intravenous ibuprofen on intraoperative analgesic efficacy in 3. molar tooth extraction

Secondary

Measure	Time frame	Description
postoperative pain as assessed by visual analogue scale	5 month	postoperative analgesic contribution of preemptively administered intravenous ibuprofen.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026