Epithelioid Hemangioma of Bone And Soft Tissue

Epithelioid Hemangioma of Bone And Soft Tissue: a Benign Tumor With Metastatic Potential

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03169595

Acronym

EE-META

Enrollment

Registered

2017-05-30

Start date

2015-10-07

Completion date

2017-05-17

Last updated

2017-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Epithelioid Hemangioma, Epithelioid Hemangioma of Bone

Brief summary

The controversy surrounding epithelioid hemangioma diagnosis stems from its somewhat aggressive clinical characteristics, including multifocal presentation and occasional lymph node involvement. The investigators reviewed the clinicopathologic and radiologic characteristics of bone and soft tissue epithelioid hemangioma in patients treated at our institution with available tissue for molecular testing. The hypothesis is that epithelioid hemangioma may present with multifocal involvement and rare loco-regional lymph node metastasis, but it remains a benign tumor with excellent prognosis.

Detailed description

The investigators retrospectively reviewed patients treated for epithelioid hemangioma of the bone and soft tissue in a single insitution. The purpose of this study is to evaluate the pathological, clinical, and radiological characteristics of epithelioid hemangioma arising within bone and soft tissue, in the first cohort of cases where the definitive diagnosis is supplemented by molecular techniques. The hypothesis is that the improved knowledge regarding this rare entity can more definitively elucidate the benign biology of epithelioid hemangioma.

Interventions

PROCEDURESurgery

Patients affected by epithelioid hemangioma treated with surgery

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* patients with epithelioid hemangioma of bone and soft tissue in the extremities and pelvis

Exclusion criteria

* patients with epithelioid hemangioma of bone and soft tissue in the spine

Design outcomes

Primary

Measure	Time frame	Description
Multifocal presentation of patients with epithelioid hemangioma of bone and soft tissue without producing a fatal outcome	2 years	The investigators defined multifocal presentation the presence of secondary lesions by imaging at presentation of the disease or during follow-up.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026