Quantification of Fetal Brains' Sulci Along Gestation

Detecting and Quantifying Sulci and White Matter in Fetus' Brain Along the Third Stage of Gestation

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03168932

Enrollment

150

Registered

2017-05-30

Start date

2017-01-01

Completion date

2018-01-31

Last updated

2017-06-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fetal Brain Injury

Brief summary

Gyrogenesis is an ontogenic process that transforms the smooth (lissencephalic) cortex toward its mature, convolved (gyrencephalic) state. A tortuous, branching and deepening pattern of sulci and fissures outlines for a well-developed cortex. The aim of this study is to find an algorithm that can detect the sulci in ultrasound images of fetus' brain and measure the length of it. This algorithm can be used for research demands like learning the development of the brain from embryo stages until the birth of the baby

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* Pregnant women between the ages of 18-35 * Gestational age between 25-40 weeks * Low risk pregnancies

Exclusion criteria

* Multiple gestation * Fetal brain abnormality

Design outcomes

Primary

Measure	Time frame	Description
morphological changes of the developing fetal brain	9 months	Ultrasound measurements of the fetal brain sulcation by a computerized algorithm

Countries

Israel

Outcome results