Clinical Application of Personal Designed 3D Printing Implants in Bone Defect Restoration

Shenzhen Hospital of Southern Medical University

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03166917

Enrollment

300

Registered

2017-05-25

Start date

2017-07-01

Completion date

2021-12-31

Last updated

2017-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Defect; Internal Prosthetic Device, Implants and Grafts, Orthopedic, Bone Graft

Brief summary

Objective: Clinical application of 3D printing implant in bone defect treatment. Study design: multicenter randomized controlled study . Methods:patients randomly grouped according to register number into internal fixation and bone graft group and 3D printing group. Reconstruct 3D models ,evaluate models preoperatively , simulate surgery in computer,design 3D implant, and 3D print implants,perform surgery with 3D implants to achieve the greatest degree of physiological reconstruction.Evaluate surgical efficacy .

Interventions

PROCEDURE3D printing implant

3D printing implants in bone defect

PROCEDUREautogenous bone grafting

3D printing implants in bone defect

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* Open fracture with bone defect * Burst fracture of spine with bone defect * Bone tumor with bone defect * Bone tuberculosis with bone defect * Nonunion with bone defect

Exclusion criteria

* Patients who can not tolerate anesthesia and surgery due to severe impairment of heart and lung function * Systemic or local infection

Design outcomes

Primary

Measure	Time frame
operative time	3 years

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026