Brain Tumor
Conditions
Brief summary
Although the Magnetic resonance imaging with contrast is the gold standard for diagnosis of intra axial brain masses. The conventional Magnetic resonance imaging appearances of intra axial brain masses can be non-specific and even the use of contrast agent is of limited benefit. Contrast enhancement reflects only disruption of blood brain barrier. One third of high-grade malignancies are non-enhanced and may non-neoplastic lesions show contrast enhancement. Reliable differentiation of neoplastic from non-neoplastic brain masses, or of high grade from low grade tumor, is difficult with conventional Magnetic resonance imaging
Interventions
injection of gadolinium contrast then acquisition of images with magnetic resonance imaging then spectroscopy
Sponsors
Study design
Eligibility
Inclusion criteria
1. Inclusion criteria: \* An intra axial space occupying lesion/lesions detected on conventional structural imaging 2.
Exclusion criteria
* MRI contraindications (as pace maker or claustrophobia). * Contrast hypersensitivity * Impaired renal function. * Pediatric age group
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of patients with malignant masses | 1 hour | sensitivity of the magnetic resonance spectroscopy in diagnosis of brain malignant masses |
Countries
Egypt