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Sodium Bicarbonate Supplementation in Athletes

The Effect of Sodium Bicarbonate Supplementation on Physical Capacity and Body Composition in Trained Athletes

Status
Completed
Phases
Phase 3
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03165357
Enrollment
26
Registered
2017-05-24
Start date
2015-10-10
Completion date
2016-04-05
Last updated
2017-05-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sport, Supplementation

Keywords

Crossfit, Sodium bicarbonate, Physical capacity

Brief summary

The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on body composition, physical capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Detailed description

Sodium bicarbonate (NaHCO3) was proposed as an ergogenic agent, because it improves high-intensity and resistance exercise performance. Until now the major limitation to NaHCO3 supplementation has been the gastrointestinal (GI) side effects. Therefore, this study aims to examine the effect of chronic, progressive- dose NaHCO3 ingestion on physical capacity, body composition and concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.

Interventions

DIETARY_SUPPLEMENTPlacebo treatment

Sponsors

Poznan University of PhysED
CollaboratorINDIV
Poznan University of Life Sciences
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
20 Years to 43 Years
Healthy volunteers
Yes

Inclusion criteria

* written consent to participate, * a current medical clearance to practice sports, * training experience: at least 2 years (of CrossFit training), * minimum of 3 workout sessions (CrossFit) a week, * 20-43 years.

Exclusion criteria

* current injury, * any health-related contraindication, * declared general feeling of being unwell, * unwilling to follow the study protocol.

Design outcomes

Primary

MeasureTime frameDescription
Changes in aerobic capacity after sodium bicarbonate supplementationBaseline and after 10 daysThe incremental cycling test (ICT)
Changes in specific performance capacity after sodium bicarbonate supplementationBaseline and after 10 daysThe CrossFit-specific physical fitness test: Fight Gone Bad (FGB)

Secondary

MeasureTime frameDescription
Changes in blood glucose and hemoglobin concentration after sodium bicarbonate supplementationBaseline and after 10 daysHemoglobin (Hb) \[g/dl\] and glucose \[g/dl\] concentration analysis
Changes in blood hematocrit levels after sodium bicarbonate supplementationBaseline and after 10 daysHematocrit (HCT) \[%\] level analysis
Changes in fat mass and fat free mass after sodium bicarbonate supplementationBaseline and after 10 daysFat mass (kg) and fat free mass (kg) analysis
Changes of creatine kinase and lactate dehydrogenase activity in blood after sodium bicarbonate supplementationBaseline and after 10 daysCreatine kinase \[U/L\] and lactate dehydrogenase \[U/L\] activity analysis
Changes of lactate and pyruvate concentration in blood after sodium bicarbonate supplementationBaseline and after 10 daysLactate \[mmol/L\] and pyruvate \[mmol/L\] concentration analysis
Changes of red and white blood cell concentration in blood after sodium bicarbonate supplementationBaseline and after 10 daysRed blood cells (RBC) \[mln/mm³\] and white blood cells (WBC) \[mln/mm³\] concentration analysis

Countries

Poland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026