Gastroduodenal Ulcer, Marginal Ulcer, Peptic Ulcer Hemorrhage
Conditions
Keywords
Gastroduodenal Ulcer, Marginal Ulcer, Peptic Ulcer Hemorrhage, Peptic Ulcer
Brief summary
Determining the efficacy of low dose of PPI in management acute peptic ulcer bleeding
Detailed description
Determining the efficacy of low dose meaning 40 mg of omeprazole twice in management acute peptic ulcer bleeding
Interventions
DRUGOmeprazole 40 MG
Omperazole 40 mg twice daily
Sponsors
Damascus Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Inclusion criteria
Criteria: Inclusion Criteria: High risk ulcers defined according to the Forrest classification With respect to high-risk stigmata, active bleeding was defined as a continuous blood spurting (Forrest IA) oozing (Forrest IB) from the ulcer base. A non-bleeding visible vessel at endoscopy was defined as a discrete protuberance at the ulcer base(Forrest IIA). An adherent clot was one that was resistant to forceful irrigation or suction (Forrest IIB).
Exclusion criteria
ulcer was malignant non ulcerative bleeding such as angiodysplasia , a Mallory-Weiss tear
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Morality | within 1 week | Determination of mortality rate from ulcer bleeding |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Rebleeding | within 1 week | Determination of the percentage of the return of bleeding represented by recurrent melena (black, tarry stool) or recurrent Hematemesis or coffee-ground emesis or recurrent hematochezia after begin treatment |
| need for surgery | within 1 week | Determine the Surgery rate for treatment Bleeding ulcers within a week |
| Length of hospital stay | within 1 month | Determining the length of stay in the hospital |
| Blood transfusions | within 1 week | number of transfusion blood unites during admission |
Countries
Syria
Outcome results
None listed