How Astigmatism Influences Corneal Biomechanics and Intraocular Pressure

Impact of Preoperative Astigmatism on Corneal Biomechanics and Accurate Intraocular Pressure Measurement After Micro-incision Phacoemulsification

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03162471

Enrollment

Registered

2017-05-22

Start date

2005-05-01

Completion date

2016-12-01

Last updated

2017-05-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract Senile, Corneal Astigmatism, Intraocular Pressure

Keywords

Corneal astigmatism, Cataract surgery, Corneal hysteresis, Corneal resistance factor, Intraocular pressure

Brief summary

The aim of the study was to identify whether preoperative corneal astigmatism can influence corneal biomechanics and the assessment of intraocular pressure (IOP) following micro-incision phacoemulsification.

Interventions

DIAGNOSTIC_TESTnon-contact measurement of intraocular pressure

Non-contact measurement of corneal biomechanical properties and intraocular pressure with an Ocular Response Analyzer. Parameters measured: corneal hysteresis (CH), corneal resistance factor (CRF), Goldman-correlated IOP (IOPg), corneal compensated IOP (IOPcc) and waveform score (WS).

Study design

Observational model

OTHER

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

52 Years to 90 Years

Healthy volunteers

Inclusion criteria

* diagnosis and qualification for cataract surgery, corneal astigmatism of equal to or less than 2.25 Dcyl

Exclusion criteria

* corneal astigmatism higher than 2.25 Dcyl, history of any other corneal disease (infection, trauma, ulceration, autoimmune inflammation, Fuchs Dystrophy, keratoconus, corneal scars, preoperative insufficiency of corneal endothelium), glaucoma and chronic use of non-glaucoma eye drops, blepharitis, dry eye, use of contact lenses diabetes or a history of corneal refractive surgery

Design outcomes

Primary

Measure	Time frame	Description
change of corneal compensated IOP (IOPcc)	Parameter measured preoperatively and one day, one week, one month postoperatively	Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.

Secondary

Measure	Time frame	Description
change of corneal hysteresis (CH)	Parameter measured preoperatively and one day, one week, one month postoperatively	Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.
change of corneal resistance factor (CRF)	Parameter measured preoperatively and one day, one week, one month postoperatively	Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.
change of Goldman-correlated IOP (IOPg)	Parameter measured preoperatively and one day, one week, one month postoperatively	Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.
change of waveform score (WS)	Parameter measured preoperatively and one day, one week, one month postoperatively	Intraocular pressure and corneal biomechanical properties were measured using an Ocular Response Analyzer.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026