Diagnosis
Conditions
Keywords
CBCT, Bone quality, Renal failure
Brief summary
This study will be observational study. The goal of this study is to evaluate the quality of mandible and to assess the correlation between the jaw bone quality in a sample of Egyptian patients with chronic renal failure and duration of dialysis using CBCT.
Detailed description
This study will be observational study. The goal of this study is to evaluate the quality of mandible and to assess the correlation between the jaw bone quality in a sample of Egyptian patients with chronic renal failure and duration of dialysis using CBCT. Twenty-six subjects will be included in this study. These will comprise (13) CKD patients the study group and (13) healthy patients the control group recommended for CBCT imaging for implant placement. The control group will be selected from the Prosthodontic department and Oral Medicine department of Faculty of Oral and Dental Medicine, Cairo University, the study group will be selected from Nephrology and the artificial kidney unit El Kasr -Al Ain Hospital, Cairo University.
Interventions
OTHERCBCT imaging
CBCT imaging of participants, then take measurement by radiomorphometric indices
Sponsors
Cairo University
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No
Inclusion criteria
* End stage renal failure (in study group) * Undergone hemo-dialysis, three times/week (in study group) * Duration of dialysis (≥1 year) (in study group) * PTH (140-630) * Age group (18-40 years) * Mandible * Free from any other systemic disease affecting the bone quality * Egyptian population
Exclusion criteria
* Early stage of renal disease * Patients with diabetes, hyperthyroidism, postmenopausal osteoporosis * Maxilla * Other language * Completely Edentulous patients.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mandibular cortical index(MCI) | Five months | Mandibular cortical index (MCI) is a qualitative index that determines the porosity degree of the lower cortical border of the mandible distal to the mental foramen.The lower border of the mandible can be classified into a three point scale according to MCI, C1: the cortex is sharp on both sides; C2: the cortex had semilunar defects(lacunar resorption) and c3: cortex is clearly porous |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Anti-gonial index(AI) | Five months | A quantitative index measure the cortical width in the region that is anterior to the gonion |
| Mental index(MI) | Five months | The quantitative index that used for cortical width measurement at the mental foramen region |
| Panoramic mandibular index(PMI) | Fivemonths | Measure the mandibular cortical thickness in relation to the distance between the mental foramen and the inferior border of mandible |
Contacts
Primary ContactEman M Mohamed, MSc
Outcome results
None listed