Calculation of Platelet-rich Plasma Preparation Yield

Calculation of Platelet-rich Plasma Preparation Yield From Baseline CBC Platelet Count

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03161743

Enrollment

Registered

2017-05-22

Start date

2017-06-30

Completion date

2018-05-31

Last updated

2017-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Platelet-rich Plasma Production

Keywords

platelet-rich plasma, platelet

Brief summary

This is a study to determine 1) the consistency of platelet-rich plasma produced by several methods, and 2) whether the platelet content of platelet-rich plasma can be accurately estimated from a baseline CBC platelet count.

Detailed description

In the first phase of this study a baseline CBC platelet count will be performed on each subject and then platelet-rich plasma (PRP) prepared from the same blood sample by six different methods. The platelet count will be measured in each PRP preparation and compared to the CBC platelet count to determine the platelet yield for each method. In the second phase of the study a baseline CBC platelet count will be performed on each subject and then platelet-rich plasma (PRP) prepared from the same blood sample by six different methods. The CBC platelet count will be used to calculate the estimated platelet content of each sample/method based on the platelet yields determined in the first phase. The platelet count will be measured in each PRP preparation and compared to the estimated platelet content to determine the predictive accuracy for each method.

Interventions

PROCEDUREvenipuncture

blood draw for the purpose of determining the platelet concentration in PRP

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

21 Years to 80 Years

Healthy volunteers

Yes

Inclusion criteria

* English speaking

Exclusion criteria

* platelet count \< 150,000 * platelet count \> 350,000 * History of blood disorder * History of altered platelet function * History of chemotherapy or radiation therapy

Design outcomes

Primary

Measure	Time frame	Description
Platelet yield	within 8 hours of blood draw	the number of platelets in a PRP sample as a percentage of the number of platelets in the blood from which the PRP was prepared.
Platelet yield estimate accuracy	within one month of final data collection	standard deviation of the difference between the estimated platelet yield and the actual platelet yield.

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026