Healthy
Conditions
Keywords
Omega-3 Index, Cellular metabolism, EPA Monoglyceride, Quality of life
Brief summary
Determine whether personal optimization of the Omega-3 index improves cellular metabolism and quality of life (according to the SF-36 form).
Interventions
DIETARY_SUPPLEMENTMAG-EPA
Based on the result of the participant's Omega-3 index obtained from the blood sampling of visit 1, the daily dose of MAG-EPA will be adjusted to obtain an Omega-3 Index of 8.
Sponsors
Université du Québec à Rimouski
SCF Pharma
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Prospective, single arm trial where each participant receives a personalized dose
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Participant aged 19 or over * Available for the entire duration of the study and willing to participate on the basis of the information provided in the FIU duly read and signed.
Exclusion criteria
* Allergy known to fish * Pregnant women who breast-feed or test positive for pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Omega-3 Index | 8 weeks | Achievement of an omega-3 index of 8. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of life | 8 weeks | Determine whether the achievement of the optimal level of the Omega-3 index results in an improvement in quality of life (according to Form SF-36) |
| Heart rate | 8 weeks | Confirm the link between the optimal omega-3 index and heart rate (bpm) |
| Total Cholesterol | 8 weeks | Confirm the link between the optimal omega-3 index and total cholesterol (in mmol/L) |
| Triglycerides | 8 weeks | Confirm the link between the optimal omega-3 index and triglycerides level (in mmol/L) |
| Cellular metabolism | 8 weeks | To determine whether the achievement of the optimal level of the omega-3 index results in an improvement in the white blood cell energy metabolism |
| LDL-cholesterol | 8 weeks | Confirm the link between the optimal omega-3 index and LDL-cholesterol (in mmol/L) |
| Alanine aminotransferase | 8 weeks | Confirm the link between the optimal omega-3 index and alanine aminotransferase (in U/L |
| HDL-cholesterol | 8 weeks | Confirm the link between the optimal omega-3 index and HDL-cholesterol (in mmol/L) |
| Bilirubin | 8 weeks | Confirm the link between the optimal omega-3 index and Bilirubin (in µmol/L) |
| Albumin | 8 weeks | Confirm the link between the optimal omega-3 index and Albumin (in g/L) |
| C-reactive protein | 8 weeks | Confirm the link between the optimal omega-3 index and C-reactive protein (in mg/L) |
| Apolipoprotein B | 8 weeks | Confirm the link between the optimal omega-3 index and Apolipoprotin B (in mmol/L) |
| Erythrocyte sedimentation rate | 8 weeks | Confirm the link between the optimal omega-3 index and the erythrocyte sedimentation rate (in min) |
| Systolic blood pressure | 8 weeks | Confirm the link between the optimal omega-3 index and the systolic blood pressure (in mm Hg) |
| Diastolic blood pressure | 8 weeks | Confirm the link between the optimal omega-3 index and the diastolic blood pressure (in mm Hg) |
| Aspartate aminotransferase | 8 weeks | Confirm the link between the optimal omega-3 index and aspartate aminotransferase (in U/L) |
Countries
Canada
Outcome results
None listed