Major Abdominal Surgeries
Conditions
Brief summary
safety and efficacy of intrathecal morphine in post operative pain relief in pediatric patients undergoing major abdominal cancer surgeries using different doses of intrathecal morphine (2 μg/kg , 5 μg/kg ,10 μg/kg).
Detailed description
After obtaining approval of the local ethics committee of faculty of medicine, Assiut University , Assiut , Egypt , and parent's written informed consent, This randomized double -blinded prospective study conducted on ( 45 ) pediatric patients aged 3-12 years , weighting between 10-30 kg , and of American Society of Anesthesiologists (ASA) physical status I and II scheduled for major abdominal surgeries
Interventions
DRUGIntrathecal Morphine
Intrathecal administration of Morphine in children undergoing major abdominal surgeries
Sponsors
Assiut University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
3 Years to 12 Years
Healthy volunteers
No
Inclusion criteria
* weight between 10-30 kg , * American Society of Anesthesiologists (ASA) I - II * major abdominal surgeries
Exclusion criteria
* Children with sacral bone abnormalities * spina bifida * coagulopathy * mental delay or retardation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| visual analog scale | 24 hours postoperative . | 0- 10 in cm score range will be used to assess pain |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| rams y sedation score | 24 hours | 0-4 score will be used |
Countries
Egypt
Outcome results
None listed