Prehabilitation, Respiratory Therapy, Thoracic Surgery
Conditions
Keywords
Inspiratory muscle training, Systemic Inflammatory Response Syndrome
Brief summary
This study evaluates the impact of preoperative high-intensity inspiratory muscle training (IMThi) before cardiac surgery on perioperative inflammatory response. Half participants will receive high intensity inspiratory muscle training and the others a sham inspiratory muscle therapy.
Interventions
OTHERPrehabilitation with inspiratory muscle training
3 to 6 weeks of two times a day inspiratory muscle training at 80% of the Maximum Inspiratory Pressure.
Sponsors
University Hospital, Angers
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Waiting for thoracic surgery with valve replacement * Preoperative surgeon consultation between 3 and 6 weeks before surgery
Exclusion criteria
* Patient with antecedent of lung surgery * Patient with neuromuscular or neurovascular disease * Non anticipated surgery with a time between surgeon consultation and surgery inferior to 3 weeks. * Inhability to do the preoperative exercises
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Preoperative STNFr1 level | Outcome is evaluated at the training initiation and re evaluated 24hours before the surgery | Post training and preoperative Serum concentration of the SRNFr1 cytokine. |
Countries
France
Outcome results
None listed